diff --git a/docs/sql/migrations/2026-11-12-remove-lab-sample-processing-menu.sql b/docs/sql/migrations/2026-11-12-remove-lab-sample-processing-menu.sql
new file mode 100644
index 00000000..20a9c3d3
--- /dev/null
+++ b/docs/sql/migrations/2026-11-12-remove-lab-sample-processing-menu.sql
@@ -0,0 +1,50 @@
+-- Issue #100：移除多余一级菜单「实验室样本处理数据」及其子菜单/按钮
+-- 软删除 sys_menu 与对应 sys_role_menu；不影响质检管理下 lab-sample-process 台账
+-- MySQL 5.7，可重复执行
+
+-- 1) 角色菜单授权
+UPDATE sys_role_menu rm
+JOIN sys_menu m ON m.id = rm.menu_id
+SET rm.del_flag = 1,
+    rm.update_by = 'migration',
+    rm.update_time = NOW()
+WHERE rm.del_flag = 0
+  AND (
+    m.perms IN (
+      'menu:lab-sample-processing',
+      'lab:sample-processing:list',
+      'lab:sample-processing:market:edit',
+      'lab:sample-processing:production:edit',
+      'lab:sample-processing:qc:edit',
+      'lab:sample-processing:manager'
+    )
+    OR m.path IN (
+      '/lab-sample-processing',
+      'lab-sample-processing/hsc',
+      'lab-sample-processing/ubmc',
+      'lab-sample-processing/msc'
+    )
+  );
+
+-- 2) 按钮 / 子菜单 / 一级菜单（先叶子后父级，同批软删即可）
+UPDATE sys_menu
+SET del_flag = 1,
+    update_by = 'migration',
+    update_time = NOW()
+WHERE del_flag = 0
+  AND (
+    perms IN (
+      'menu:lab-sample-processing',
+      'lab:sample-processing:list',
+      'lab:sample-processing:market:edit',
+      'lab:sample-processing:production:edit',
+      'lab:sample-processing:qc:edit',
+      'lab:sample-processing:manager'
+    )
+    OR path IN (
+      '/lab-sample-processing',
+      'lab-sample-processing/hsc',
+      'lab-sample-processing/ubmc',
+      'lab-sample-processing/msc'
+    )
+  );
diff --git a/web-admin/src/router/modules/sqxp.ts b/web-admin/src/router/modules/sqxp.ts
index aafee319..32331f8e 100644
--- a/web-admin/src/router/modules/sqxp.ts
+++ b/web-admin/src/router/modules/sqxp.ts
@@ -1313,59 +1313,6 @@ export const sqxpAdminRoutes: AppRouteRecord[] = [
     ]
   },
 
-  // ═══════════════════════════════════════════════════════════════════════════
-  // 3b. 实验室样本处理数据 (menu:lab-sample-processing)
-  // ═══════════════════════════════════════════════════════════════════════════
-  {
-    id: 'TOP0000000000000000000000000000L1',
-    name: 'LabSampleProcessing',
-    path: '/lab-sample-processing',
-    component: '/index/index',
-    meta: {
-      title: '实验室样本处理数据',
-      icon: 'ri:test-tube-line',
-      keepAlive: false,
-      isTopMenu: true,
-      menuCode: 'menu:lab-sample-processing',
-      roles: ['admin']
-    },
-    children: [
-      {
-        id: 'LAB00000000000000000000000000001',
-        name: 'LabSampleProcessingHsc',
-        path: 'hsc',
-        component: '/lab-sample-processing/hsc/index',
-        meta: {
-          title: '造血干细胞数据',
-          keepAlive: true,
-          menuCode: 'lab:sample-processing:list'
-        }
-      },
-      {
-        id: 'LAB00000000000000000000000000002',
-        name: 'LabSampleProcessingUbmc',
-        path: 'ubmc',
-        component: '/lab-sample-processing/ubmc/index',
-        meta: {
-          title: '单个核数据',
-          keepAlive: true,
-          menuCode: 'lab:sample-processing:list'
-        }
-      },
-      {
-        id: 'LAB00000000000000000000000000003',
-        name: 'LabSampleProcessingMsc',
-        path: 'msc',
-        component: '/lab-sample-processing/msc/index',
-        meta: {
-          title: '脐带间充质干细胞数据',
-          keepAlive: true,
-          menuCode: 'lab:sample-processing:list'
-        }
-      }
-    ]
-  },
-
   // ═══════════════════════════════════════════════════════════════════════════
   // 4. 运营支撑 (menu:operations)
   // 二级菜单：系统基础信息、运营支撑