zkxw/backend/app/crud/pilot_infusion_schedule_mgmt.py

"""中试输注计划管理 CRUD（输注计划列表、详情、状态变更、编辑）"""
from __future__ import annotations

import json
from datetime import datetime
from typing import Any, Dict, List, Optional

from sqlalchemy import and_, desc, func, or_
from sqlalchemy.orm import Session

from app.core.utils import generate_uuid
from app.crud.child_row_sync import sync_child_rows
from app.models.models import (
    BizChannelAgreementProductPrice,
    BizChannelServiceOrder,
    BizChannelServiceOrderProduct,
    BizChannelServiceOrderTxn,
    BizPilotApplication,
    BizPilotInfusionPlan,
    BizPilotInfusionSchedule,
    BizPilotInfusionScheduleProduct,
    BizPilotPatient,
    BizProductionWorkOrder,
    BizQcWorkOrder,
)
from app.crud.pilot_service import (
    _get_or_create_channel_account,
    _reduce_channel_product_quota,
    _resolve_agreement_price_cell_type,
)
from app.crud import outbound_handover as handover_svc
from app.crud import outbound_release_review as orr_svc
from app.crud import pilot_infusion_confirm as confirm_svc


# ────────────────────────────────────────────
# Status transition map
# ────────────────────────────────────────────

VALID_TRANSITIONS: Dict[str, set] = {
    "dtz": {"yrqr", "yqx"},
    "yrqr": {"ywc", "yqx"},
}

QC_VALID_TRANSITIONS: Dict[str, set] = {
    "dzc": {"yzj", "yqx"},
}


# ────────────────────────────────────────────
# Helpers: _row_to_dict
# ────────────────────────────────────────────


def _row_to_dict_schedule(
    row,
    application=None,
    plan=None,
    patient=None,
    products=None,
    service_order=None,
    plan_meta: Optional[Dict[str, Any]] = None,
) -> Dict[str, Any]:
    course = _resolve_course_display(row, plan, plan_meta)
    d: Dict[str, Any] = {
        "id": row.id,
        "infusionPlanId": row.infusion_plan_id or "",
        "sortNo": course.get("sortNo"),
        "totalCourseCount": course.get("totalCourseCount"),
        "cellType": row.cell_type or "",
        "specText": row.spec_text or "",
        "packageId": getattr(row, "package_id", None) or "",
        "packageText": getattr(row, "package_text", None) or "",
        "infusionTime": row.infusion_time.strftime("%Y-%m-%d %H:%M:%S") if row.infusion_time else "",
        "infusionLocation": row.infusion_location or "",
        "infusionMethod": row.infusion_method or "",
        "scheduleStatus": row.schedule_status or "",
        "infusionStatus": row.infusion_status or "",
        "cancelReason": row.cancel_reason or "",
        "qcStatus": row.qc_status or "",
        "attachments": row.attachments or "",
        "remark": row.remark or "",
        "createTime": row.create_time.strftime("%Y-%m-%d %H:%M:%S") if row.create_time else "",
        "updateTime": row.update_time.strftime("%Y-%m-%d %H:%M:%S") if row.update_time else "",
    }

    if application:
        d["applicationNo"] = application.application_no or ""
        d["applicationName"] = application.application_name or ""
        d["applicationStatus"] = application.application_status or ""
        d["channelName"] = application.channel_name or ""
        d["channelId"] = application.channel_id or ""
        d["pilotApplicationId"] = application.id or ""
        d["channelServiceOrderId"] = application.channel_service_order_id or ""
        d["projectTitle"] = application.project_title or ""
        d["customerName"] = application.customer_name or ""
        d["bizType"] = application.biz_type or "pilot_service"
    else:
        d["applicationNo"] = ""
        d["applicationName"] = ""
        d["applicationStatus"] = ""
        d["channelName"] = ""
        d["channelId"] = ""
        d["pilotApplicationId"] = ""
        d["channelServiceOrderId"] = ""
        d["projectTitle"] = ""
        d["customerName"] = ""
        d["bizType"] = ""

    if plan:
        d["channelAgreementId"] = plan.channel_agreement_id or ""
    else:
        d["channelAgreementId"] = ""

    if patient:
        d["patientName"] = patient.patient_name or ""
        d["patientSex"] = patient.sex or ""
        d["patientAge"] = patient.age
    else:
        d["patientName"] = ""
        d["patientSex"] = ""
        d["patientAge"] = None

    if service_order:
        d["orderType"] = service_order.order_type or ""
        d["channelServiceOrderName"] = service_order.order_name or ""
    else:
        d["orderType"] = ""
        d["channelServiceOrderName"] = ""

    if products is not None:
        d["products"] = products
    else:
        d["products"] = []

    return d


def _row_to_dict_product(row) -> Dict[str, Any]:
    return {
        "id": row.id,
        "priceId": row.price_id or "",
        "projectCode": row.project_code or "",
        "projectName": row.project_name or "",
        "cellTypeName": row.cell_type_name or "",
        "specText": row.spec_text or "",
        "packageId": getattr(row, "package_id", None) or "",
        "packageText": getattr(row, "package_text", None) or "",
        "agreementPrice": float(row.agreement_price) if row.agreement_price is not None else None,
        "actualPrice": float(row.actual_price) if row.actual_price is not None else None,
        "quantity": row.quantity if row.quantity is not None else 1,
        "remark": row.remark or "",
        "productStatus": row.product_status or "",
        "status": row.product_status or "",
    }


def _get_plan_schedule_course_meta(
    db: Session, plan_ids: List[str], tenant_no: str
) -> Dict[str, Dict[str, Any]]:
    """按输注方案汇总：计划条数、各计划内每条 schedule 的疗程序号（1 起）。"""
    unique_ids = list({pid for pid in plan_ids if pid})
    if not unique_ids:
        return {}

    rows = (
        db.query(BizPilotInfusionSchedule)
        .filter(
            BizPilotInfusionSchedule.infusion_plan_id.in_(unique_ids),
            BizPilotInfusionSchedule.tenant_no == tenant_no,
            BizPilotInfusionSchedule.del_flag == 0,
        )
        .order_by(
            BizPilotInfusionSchedule.infusion_plan_id.asc(),
            BizPilotInfusionSchedule.order_num.asc(),
            BizPilotInfusionSchedule.create_time.asc(),
        )
        .all()
    )

    meta: Dict[str, Dict[str, Any]] = {}
    by_plan: Dict[str, List[BizPilotInfusionSchedule]] = {}
    for row in rows:
        by_plan.setdefault(row.infusion_plan_id, []).append(row)

    for plan_id, schedules in by_plan.items():
        sort_no_by_id: Dict[str, int] = {}
        for idx, sch in enumerate(schedules):
            order_num = sch.order_num if sch.order_num is not None else 0
            sort_no_by_id[sch.id] = order_num if order_num > 0 else idx + 1
        meta[plan_id] = {
            "scheduleCount": len(schedules),
            "sortNoByScheduleId": sort_no_by_id,
        }
    return meta


def _resolve_course_display(
    row: BizPilotInfusionSchedule,
    plan: Optional[BizPilotInfusionPlan],
    plan_meta: Optional[Dict[str, Any]] = None,
) -> Dict[str, Optional[int]]:
    sort_no: Optional[int] = None
    total: Optional[int] = None

    if plan_meta:
        sort_no = plan_meta.get("sortNoByScheduleId", {}).get(row.id)
        plan_total = plan.total_course_count if plan else None
        if plan_total is not None and plan_total > 0:
            total = int(plan_total)
        else:
            total = int(plan_meta.get("scheduleCount") or 0) or None
    elif plan and row.infusion_plan_id:
        order_num = row.order_num if row.order_num is not None else 0
        if order_num > 0:
            sort_no = int(order_num)
        plan_total = plan.total_course_count
        if plan_total is not None and plan_total > 0:
            total = int(plan_total)

    if sort_no is None or sort_no <= 0:
        order_num = row.order_num if row.order_num is not None else 0
        sort_no = int(order_num) if order_num > 0 else None

    return {"sortNo": sort_no, "totalCourseCount": total if total and total > 0 else None}


def _get_products_for_schedule(db: Session, schedule_id: str, tenant_no: str) -> List[Dict[str, Any]]:
    rows = (
        db.query(BizPilotInfusionScheduleProduct)
        .filter(
            BizPilotInfusionScheduleProduct.infusion_schedule_id == schedule_id,
            BizPilotInfusionScheduleProduct.tenant_no == tenant_no,
            BizPilotInfusionScheduleProduct.del_flag == 0,
        )
        .order_by(
            BizPilotInfusionScheduleProduct.order_num.asc(),
            BizPilotInfusionScheduleProduct.create_time.asc(),
        )
        .all()
    )
    return [_row_to_dict_product(r) for r in rows]


# ────────────────────────────────────────────
# List (Paginated, Multi-table JOIN)
# ────────────────────────────────────────────


def list_infusion_schedules_mgmt(
    db: Session,
    tenant_no: str,
    page: int = 1,
    page_size: int = 10,
    keyword: Optional[str] = None,
    infusion_status: Optional[str] = None,
    qc_status: Optional[str] = None,
    infusion_time_start: Optional[str] = None,
    infusion_time_end: Optional[str] = None,
    biz_type: Optional[str] = None,
) -> Dict[str, Any]:
    sch = BizPilotInfusionSchedule
    plan = BizPilotInfusionPlan
    app = BizPilotApplication
    pat = BizPilotPatient
    prod = BizPilotInfusionScheduleProduct

    q = (
        db.query(sch)
        .outerjoin(plan, and_(sch.infusion_plan_id == plan.id, plan.del_flag == 0))
        .outerjoin(app, and_(plan.pilot_application_id == app.id, app.del_flag == 0))
        .outerjoin(pat, and_(app.id == pat.pilot_application_id, pat.del_flag == 0))
        .filter(
            sch.tenant_no == tenant_no,
            sch.del_flag == 0,
        )
    )

    bt = (biz_type or "").strip()
    if bt:
        q = q.filter(app.biz_type == bt)

    # keyword: application_no, channel_name, patient_name; basic_experiment also project_title/customer_name
    if keyword:
        kw = f"%{keyword}%"
        q = q.filter(
            or_(
                app.application_no.like(kw),
                app.channel_name.like(kw),
                app.project_title.like(kw),
                app.customer_name.like(kw),
                pat.patient_name.like(kw),
            )
        )

    if infusion_status:
        statuses = [s.strip() for s in infusion_status.split(",") if s.strip()]
        if statuses:
            q = q.filter(sch.infusion_status.in_(statuses))

    if qc_status:
        qc_statuses = [s.strip() for s in qc_status.split(",") if s.strip()]
        if qc_statuses:
            q = q.filter(sch.qc_status.in_(qc_statuses))

    time_bounds = []
    if infusion_time_start:
        try:
            start_dt = datetime.strptime(infusion_time_start[:10], "%Y-%m-%d")
            time_bounds.append(sch.infusion_time >= start_dt)
        except ValueError:
            pass

    if infusion_time_end:
        try:
            end_dt = datetime.strptime(infusion_time_end[:10], "%Y-%m-%d")
            end_dt = end_dt.replace(hour=23, minute=59, second=59)
            time_bounds.append(sch.infusion_time <= end_dt)
        except ValueError:
            pass

    # 未填写输注时间的计划（申请单新建时常见）在限定时间范围时仍应可见
    if time_bounds:
        q = q.filter(or_(and_(*time_bounds), sch.infusion_time.is_(None)))

    total = q.order_by(None).with_entities(func.count(sch.id)).scalar() or 0
    page = max(1, page)
    page_size = min(max(1, page_size), 100)

    # Use distinct to avoid duplicates from JOINs
    # MySQL 5.7 不支持 NULLS LAST：先排「有输注时间」再按时间倒序，未填时间的排最后
    schedule_rows = (
        q.order_by(sch.infusion_time.is_(None), desc(sch.infusion_time), desc(sch.create_time))
        .distinct()
        .offset((page - 1) * page_size)
        .limit(page_size)
        .all()
    )

    plan_ids = [r.infusion_plan_id for r in schedule_rows if r.infusion_plan_id]
    plan_course_meta = _get_plan_schedule_course_meta(db, plan_ids, tenant_no)

    items = []
    for row in schedule_rows:
        # Fetch related data for each schedule
        plan_row = (
            db.query(BizPilotInfusionPlan)
            .filter(
                BizPilotInfusionPlan.id == row.infusion_plan_id,
                BizPilotInfusionPlan.del_flag == 0,
            )
            .first()
        )
        application = None
        patient = None
        if plan_row:
            application = (
                db.query(BizPilotApplication)
                .filter(
                    BizPilotApplication.id == plan_row.pilot_application_id,
                    BizPilotApplication.del_flag == 0,
                )
                .first()
            )
            if application:
                patient = (
                    db.query(BizPilotPatient)
                    .filter(
                        BizPilotPatient.pilot_application_id == application.id,
                        BizPilotPatient.del_flag == 0,
                    )
                    .first()
                )

        service_order = None
        if application and application.channel_service_order_id:
            service_order = (
                db.query(BizChannelServiceOrder)
                .filter(
                    BizChannelServiceOrder.id == application.channel_service_order_id,
                    BizChannelServiceOrder.del_flag == 0,
                )
                .first()
            )

        products = _get_products_for_schedule(db, row.id, tenant_no)
        plan_meta = plan_course_meta.get(row.infusion_plan_id) if row.infusion_plan_id else None
        items.append(
            _row_to_dict_schedule(
                row,
                application,
                plan_row,
                patient,
                products,
                service_order,
                plan_meta=plan_meta,
            )
        )

    schedule_ids = [item["id"] for item in items if item.get("id")]
    if schedule_ids:
        from app.crud import clinical_payment

        payment_map = clinical_payment.map_payments_by_schedule_ids(
            db, schedule_ids=schedule_ids, tenant_no=tenant_no
        )
        for item in items:
            payment = payment_map.get(item["id"])
            if not payment:
                continue
            item["payment"] = payment
            item["amount"] = payment.get("amount")
            item["payStatus"] = payment.get("payStatus")

    return {
        "list": items,
        "pagination": {"page": page, "pageSize": page_size, "total": total},
    }


# ────────────────────────────────────────────
# Detail
# ────────────────────────────────────────────


def get_infusion_schedule_detail(
    db: Session, schedule_id: str, tenant_no: str
) -> Optional[Dict[str, Any]]:
    row = (
        db.query(BizPilotInfusionSchedule)
        .filter(
            BizPilotInfusionSchedule.id == schedule_id,
            BizPilotInfusionSchedule.tenant_no == tenant_no,
            BizPilotInfusionSchedule.del_flag == 0,
        )
        .first()
    )
    if not row:
        return None

    plan_row = (
        db.query(BizPilotInfusionPlan)
        .filter(
            BizPilotInfusionPlan.id == row.infusion_plan_id,
            BizPilotInfusionPlan.del_flag == 0,
        )
        .first()
    )

    application = None
    patient = None
    if plan_row:
        application = (
            db.query(BizPilotApplication)
            .filter(
                BizPilotApplication.id == plan_row.pilot_application_id,
                BizPilotApplication.del_flag == 0,
            )
            .first()
        )
        if application:
            patient = (
                db.query(BizPilotPatient)
                .filter(
                    BizPilotPatient.pilot_application_id == application.id,
                    BizPilotPatient.del_flag == 0,
                )
                .first()
            )

    service_order = None
    if application and application.channel_service_order_id:
        service_order = (
            db.query(BizChannelServiceOrder)
            .filter(
                BizChannelServiceOrder.id == application.channel_service_order_id,
                BizChannelServiceOrder.del_flag == 0,
            )
            .first()
        )

    products = _get_products_for_schedule(db, row.id, tenant_no)
    plan_meta = None
    if row.infusion_plan_id:
        batch_meta = _get_plan_schedule_course_meta(db, [row.infusion_plan_id], tenant_no)
        plan_meta = batch_meta.get(row.infusion_plan_id)
    flat = _row_to_dict_schedule(
        row, application, plan_row, patient, products, service_order, plan_meta=plan_meta
    )

    aggregated = orr_svc.get_schedule_detail(db, schedule_id, tenant_no) or {}

    app = dict(aggregated.get("application") or {})
    app["applicationNo"] = app.get("applicationNo") or flat.get("applicationNo") or ""
    app["applicationName"] = app.get("applicationName") or flat.get("applicationName") or ""
    app["applicationStatus"] = app.get("applicationStatus") or flat.get("applicationStatus") or ""
    app["channelName"] = app.get("channelName") or flat.get("channelName") or ""
    app["orderType"] = flat.get("orderType") or ""
    app["channelServiceOrderName"] = flat.get("channelServiceOrderName") or ""
    app["channelServiceOrderId"] = flat.get("channelServiceOrderId") or ""
    app["projectTitle"] = app.get("projectTitle") or flat.get("projectTitle") or ""
    app["customerName"] = app.get("customerName") or flat.get("customerName") or ""
    if application:
        app["bizType"] = application.biz_type or "pilot_service"
        if not app.get("projectTitle"):
            app["projectTitle"] = application.project_title or ""
        if not app.get("customerName"):
            app["customerName"] = application.customer_name or ""

    plan = dict(aggregated.get("infusionPlan") or {})
    if plan_row:
        plan.setdefault("cellType", plan_row.cell_type or "")
        plan.setdefault("specText", plan_row.spec_text or "")
        plan.setdefault("totalCourseCount", plan_row.total_course_count)
        plan.setdefault("courseInterval", plan_row.course_interval or "")
        plan.setdefault("infusionStartDate", plan_row.infusion_start_date or "")

    sched = dict(aggregated.get("infusionSchedule") or {})
    sched["sortNo"] = flat.get("sortNo")
    sched["totalCourseCount"] = flat.get("totalCourseCount")
    sched["cellType"] = flat.get("cellType") or sched.get("cellType") or ""
    sched["specText"] = flat.get("specText") or sched.get("specText") or ""
    sched["packageId"] = flat.get("packageId") or sched.get("packageId") or ""
    sched["packageText"] = flat.get("packageText") or sched.get("packageText") or ""
    sched["infusionTime"] = flat.get("infusionTime") or sched.get("infusionTime") or ""
    sched["infusionLocation"] = flat.get("infusionLocation") or sched.get("infusionLocation") or ""
    sched["infusionMethod"] = flat.get("infusionMethod") or sched.get("infusionMethod") or ""
    sched["scheduleStatus"] = flat.get("scheduleStatus") or sched.get("scheduleStatus") or ""
    sched["infusionStatus"] = flat.get("infusionStatus") or sched.get("infusionStatus") or ""
    sched["qcStatus"] = flat.get("qcStatus") or sched.get("qcStatus") or ""
    sched["cancelReason"] = flat.get("cancelReason") or sched.get("cancelReason") or ""
    sched["remark"] = flat.get("remark") or ""

    patient_data = dict(aggregated.get("patient") or {})
    if patient:
        patient_data.setdefault("patientName", patient.patient_name or "")
        patient_data.setdefault("sex", patient.sex or "")
        patient_data.setdefault("age", str(patient.age) if patient.age is not None else "")
        patient_data.setdefault("phoneNo", patient.phone_no or "")
        patient_data.setdefault("idCardNo", patient.id_card_no or "")
        patient_data.setdefault("emergencyContact", patient.emergency_contact or "")
        patient_data.setdefault("emergencyPhone", patient.emergency_phone or "")
        patient_data.setdefault("clinicalDiagnosis", patient.clinical_diagnosis or "")
        patient_data.setdefault("diagnosisAttachments", patient.diagnosis_attachments or "")
        patient_data.setdefault("needCheckup", patient.need_checkup)

    result: Dict[str, Any] = {
        **aggregated,
        **flat,
        "application": app,
        "patient": patient_data,
        "infusionPlan": plan,
        "infusionSchedule": sched,
        "products": flat.get("products") or aggregated.get("products") or [],
        "productionInfo": aggregated.get("productionInfo") or {},
        "qcInfo": aggregated.get("qcInfo") or {},
        "processQcInfoList": aggregated.get("processQcInfoList") or [],
        "reviewInfo": aggregated.get("reviewInfo") or {},
        "outboundMaterial": aggregated.get("outboundMaterial") or {},
        "outboundHandover": handover_svc.get_outbound_handover_view(db, schedule_id, tenant_no),
        "infusionConfirm": confirm_svc.get_confirm_by_schedule(db, schedule_id, tenant_no) or {},
    }
    if application and (application.biz_type or "") in ("clinical_application", "basic_experiment"):
        from app.crud import clinical_payment

        payment = clinical_payment.get_payment_by_schedule(
            db, schedule_id=schedule_id, tenant_no=tenant_no
        )
        if payment:
            result["payment"] = payment
    return result


# ────────────────────────────────────────────
# Status update
# ────────────────────────────────────────────


def update_infusion_status(
    db: Session,
    schedule_id: str,
    infusion_status: str,
    cancel_reason: Optional[str],
    tenant_no: str,
    user_id: str,
) -> Dict[str, Any]:
    row = (
        db.query(BizPilotInfusionSchedule)
        .filter(
            BizPilotInfusionSchedule.id == schedule_id,
            BizPilotInfusionSchedule.tenant_no == tenant_no,
            BizPilotInfusionSchedule.del_flag == 0,
        )
        .first()
    )
    if not row:
        raise ValueError("输注计划不存在")

    current = row.infusion_status or ""
    if current not in VALID_TRANSITIONS:
        raise ValueError(f"当前状态 {current} 不允许变更")
    if infusion_status not in VALID_TRANSITIONS.get(current, set()):
        raise ValueError(f"不允许从 {current} 变更为 {infusion_status}")

    # Cancel requires reason
    if infusion_status == "yqx" and not cancel_reason:
        raise ValueError("取消时需填写取消原因")

    now = datetime.now()
    row.infusion_status = infusion_status
    row.update_by = user_id
    row.update_time = now

    if infusion_status == "yqx":
        row.cancel_reason = cancel_reason or ""
        row.schedule_status = "yqx"
        row.qc_status = "yqx"

        # 自动作废关联的未完成出库生产工单
        outbound_wo = (
            db.query(BizProductionWorkOrder)
            .filter(
                BizProductionWorkOrder.infusion_schedule_id == schedule_id,
                BizProductionWorkOrder.tenant_no == tenant_no,
                BizProductionWorkOrder.del_flag == 0,
                BizProductionWorkOrder.work_order_type == "outbound",
                BizProductionWorkOrder.work_order_status.notin_(["ywc", "yzf"]),
            )
            .first()
        )
        if outbound_wo:
            outbound_wo.work_order_status = "yzf"
            outbound_wo.update_by = user_id
            outbound_wo.update_time = now

        # 自动作废关联的未完成出库质检工单
        pending_qc_orders = (
            db.query(BizQcWorkOrder)
            .filter(
                BizQcWorkOrder.infusion_schedule_id == schedule_id,
                BizQcWorkOrder.work_order_status.notin_(["ywc", "yzf"]),
                BizQcWorkOrder.del_flag == 0,
            )
            .all()
        )
        for order in pending_qc_orders:
            order.work_order_status = "yzf"
            order.update_by = user_id
            order.update_time = now

        from app.crud.pilot_outbound_status_sync import sync_pilot_outbound_from_schedule

        sync_pilot_outbound_from_schedule(db, row, user_id=user_id)

    # Sync all related products' product_status
    product_rows = (
        db.query(BizPilotInfusionScheduleProduct)
        .filter(
            BizPilotInfusionScheduleProduct.infusion_schedule_id == schedule_id,
            BizPilotInfusionScheduleProduct.tenant_no == tenant_no,
            BizPilotInfusionScheduleProduct.del_flag == 0,
        )
        .all()
    )
    for p_row in product_rows:
        p_row.product_status = infusion_status
        p_row.update_by = user_id
        p_row.update_time = now

    db.flush()

    # If completing, trigger fee deduction
    if infusion_status == "ywc":
        _deduct_fee_on_complete(db, schedule_id, tenant_no, user_id)

    db.commit()
    db.refresh(row)
    return get_infusion_schedule_detail(db, row.id, tenant_no)


def update_qc_status(
    db: Session,
    schedule_id: str,
    qc_status: str,
    tenant_no: str,
    user_id: str,
) -> Dict[str, Any]:
    row = (
        db.query(BizPilotInfusionSchedule)
        .filter(
            BizPilotInfusionSchedule.id == schedule_id,
            BizPilotInfusionSchedule.tenant_no == tenant_no,
            BizPilotInfusionSchedule.del_flag == 0,
        )
        .first()
    )
    if not row:
        raise ValueError("输注计划不存在")

    current = row.qc_status or ""
    if current not in QC_VALID_TRANSITIONS:
        raise ValueError(f"当前质检状态 {current} 不允许变更")
    if qc_status not in QC_VALID_TRANSITIONS.get(current, set()):
        raise ValueError(f"不允许从质检状态 {current} 变更为 {qc_status}")

    now = datetime.now()
    row.qc_status = qc_status
    row.update_by = user_id
    row.update_time = now

    from app.crud.pilot_outbound_status_sync import sync_pilot_outbound_from_schedule

    sync_pilot_outbound_from_schedule(db, row, user_id=user_id)

    db.commit()
    db.refresh(row)
    return get_infusion_schedule_detail(db, row.id, tenant_no)


def _settlement_remark_marker(schedule_id: str) -> str:
    """幂等检索用标记（中文）；兼容历史英文标记 infusionScheduleId="""
    return f"输注计划ID={schedule_id}"


def _settlement_remark_markers_for_lookup(schedule_id: str) -> List[str]:
    return [_settlement_remark_marker(schedule_id), f"infusionScheduleId={schedule_id}"]


def _find_existing_settlement_txn(
    db: Session, order_id: str, schedule_id: str
) -> Optional[BizChannelServiceOrderTxn]:
    marker_filters = [
        BizChannelServiceOrderTxn.remark.like(f"%{m}%")
        for m in _settlement_remark_markers_for_lookup(schedule_id)
    ]
    return (
        db.query(BizChannelServiceOrderTxn)
        .filter(
            BizChannelServiceOrderTxn.service_order_id == order_id,
            BizChannelServiceOrderTxn.txn_type == "settlement",
            or_(*marker_filters),
            BizChannelServiceOrderTxn.txn_status != "yzf",
            BizChannelServiceOrderTxn.del_flag == 0,
        )
        .first()
    )


def _resolve_yfk_unit_price(
    db: Session, agreement_id: str, product: BizPilotInfusionScheduleProduct
) -> float:
    spec = (product.spec_text or "").strip()
    if agreement_id and (product.project_code or "").strip():
        row = (
            db.query(BizChannelAgreementProductPrice)
            .filter(
                BizChannelAgreementProductPrice.channel_agreement_id == agreement_id,
                BizChannelAgreementProductPrice.project_code == (product.project_code or ""),
                BizChannelAgreementProductPrice.spec_text == spec,
                BizChannelAgreementProductPrice.del_flag == 0,
            )
            .first()
        )
        if row and row.agreement_price is not None:
            return float(row.agreement_price)

    cell_name = (product.cell_type_name or "").strip()
    if agreement_id and cell_name:
        row = (
            db.query(BizChannelAgreementProductPrice)
            .filter(
                BizChannelAgreementProductPrice.channel_agreement_id == agreement_id,
                BizChannelAgreementProductPrice.spec_text == spec,
                BizChannelAgreementProductPrice.del_flag == 0,
                or_(
                    BizChannelAgreementProductPrice.cell_type_code == cell_name,
                    BizChannelAgreementProductPrice.cell_type_name == cell_name,
                ),
            )
            .first()
        )
        if row and row.agreement_price is not None:
            return float(row.agreement_price)

    if product.actual_price is not None:
        return float(product.actual_price)
    if product.agreement_price is not None:
        return float(product.agreement_price)
    return 0.0


def _find_service_order_product(
    db: Session, order_id: str, product: BizPilotInfusionScheduleProduct
) -> Optional[BizChannelServiceOrderProduct]:
    project_code = (product.project_code or "").strip()
    spec = (product.spec_text or "").strip()
    cell_type = (product.cell_type_name or "").strip()
    if project_code:
        row = (
            db.query(BizChannelServiceOrderProduct)
            .filter(
                BizChannelServiceOrderProduct.service_order_id == order_id,
                BizChannelServiceOrderProduct.project_code == project_code,
                BizChannelServiceOrderProduct.spec_text == spec,
                BizChannelServiceOrderProduct.del_flag == 0,
            )
            .first()
        )
        if row:
            return row
    if cell_type:
        return (
            db.query(BizChannelServiceOrderProduct)
            .filter(
                BizChannelServiceOrderProduct.service_order_id == order_id,
                BizChannelServiceOrderProduct.cell_type == cell_type,
                BizChannelServiceOrderProduct.spec_text == spec,
                BizChannelServiceOrderProduct.del_flag == 0,
            )
            .first()
        )
    return None


def _schedule_product_to_txn_item(
    product: BizPilotInfusionScheduleProduct, *, qty: int, amount: float
) -> Dict[str, Any]:
    return {
        "projectCode": product.project_code or "",
        "projectName": product.project_name or "",
        "cellType": product.cell_type_name or "",
        "specText": product.spec_text or "",
        "qty": qty,
        "amount": round(amount, 2),
    }


def _create_settlement_txn(
    db: Session,
    *,
    order: BizChannelServiceOrder,
    schedule_id: str,
    application_no: str,
    amount: float,
    products_json: List[Dict[str, Any]],
    balance_before: Optional[float],
    balance_after: Optional[float],
    tenant_no: str,
    user_id: str,
) -> BizChannelServiceOrderTxn:
    now = datetime.now()
    remark_parts = [
        "输注计划完成结算",
        _settlement_remark_marker(schedule_id),
    ]
    if application_no:
        remark_parts.append(f"申请单号={application_no}")
    txn = BizChannelServiceOrderTxn(
        id=generate_uuid(),
        service_order_id=order.id,
        txn_type="settlement",
        amount=round(amount, 2),
        txn_status="yqr",
        products_json=json.dumps(products_json, ensure_ascii=False) if products_json else None,
        remark=" ".join(remark_parts),
        balance_before=balance_before,
        balance_after=balance_after,
        finance_confirm_time=now,
        finance_confirm_by=user_id,
        finance_remark="输注计划完成自动结算",
        tenant_no=tenant_no or order.tenant_no,
        order_num=0,
        create_by=user_id,
        create_dept_id="",
        create_time=now,
        update_by=user_id,
        update_time=now,
        del_flag=0,
    )
    db.add(txn)
    db.flush()
    return txn


def _deduct_fee_on_complete(db: Session, schedule_id: str, tenant_no: str, user_id: str):
    schedule = (
        db.query(BizPilotInfusionSchedule)
        .filter(
            BizPilotInfusionSchedule.id == schedule_id,
            BizPilotInfusionSchedule.tenant_no == tenant_no,
            BizPilotInfusionSchedule.del_flag == 0,
        )
        .first()
    )
    if not schedule:
        raise ValueError("输注计划不存在")

    plan = (
        db.query(BizPilotInfusionPlan)
        .filter(
            BizPilotInfusionPlan.id == schedule.infusion_plan_id,
            BizPilotInfusionPlan.del_flag == 0,
        )
        .first()
    )
    if not plan:
        raise ValueError("输注方案不存在")

    application = (
        db.query(BizPilotApplication)
        .filter(
            BizPilotApplication.id == plan.pilot_application_id,
            BizPilotApplication.tenant_no == tenant_no,
            BizPilotApplication.del_flag == 0,
        )
        .first()
    )
    if not application:
        raise ValueError("中试申请单不存在")

    # 临床应用/基础实验走缴费模块，不走服务订单扣费
    if (application.biz_type or "") in ("clinical_application", "basic_experiment"):
        return

    if not application.channel_service_order_id:
        raise ValueError("申请单未关联渠道服务订单，无法扣费")

    order = (
        db.query(BizChannelServiceOrder)
        .filter(
            BizChannelServiceOrder.id == application.channel_service_order_id,
            BizChannelServiceOrder.del_flag == 0,
        )
        .first()
    )
    if not order:
        raise ValueError("渠道服务订单不存在")

    order_type = order.order_type or ""
    application_no = application.application_no or ""

    if _find_existing_settlement_txn(db, order.id, schedule_id):
        return

    products = (
        db.query(BizPilotInfusionScheduleProduct)
        .filter(
            BizPilotInfusionScheduleProduct.infusion_schedule_id == schedule_id,
            BizPilotInfusionScheduleProduct.tenant_no == tenant_no,
            BizPilotInfusionScheduleProduct.del_flag == 0,
        )
        .order_by(
            BizPilotInfusionScheduleProduct.order_num.asc(),
            BizPilotInfusionScheduleProduct.create_time.asc(),
        )
        .all()
    )

    if not products:
        raise ValueError("输注计划未配置细胞产品，无法完成结算，请先在编辑中维护产品明细")

    now = datetime.now()

    if order_type == "yfk":
        agreement_id = order.channel_agreement_id
        if not agreement_id:
            raise ValueError("服务订单未关联渠道协议，无法确定扣费金额")

        total_deduction = 0.0
        txn_products: List[Dict[str, Any]] = []
        for p in products:
            qty = max(1, int(p.quantity or 1))
            unit_price = _resolve_yfk_unit_price(db, agreement_id, p)
            if unit_price <= 0:
                label = p.project_name or p.cell_type_name or p.project_code or "未知产品"
                raise ValueError(f"无法确定产品「{label}」的协议单价，请检查渠道协议价格或输注计划实际单价")
            line_amount = unit_price * qty
            total_deduction += line_amount
            txn_products.append(
                _schedule_product_to_txn_item(p, qty=qty, amount=line_amount)
            )

        account = _get_or_create_channel_account(db, order.channel_id, tenant_no, user_id)
        balance_before = float(account.balance_amount) if account.balance_amount else 0

        if balance_before < total_deduction:
            raise ValueError(
                f"渠道账户余额不足，当前余额 {balance_before} 元，需扣减 {total_deduction} 元"
            )

        account.balance_amount = balance_before - total_deduction
        balance_after = float(account.balance_amount)
        account.update_by = user_id
        account.update_time = now
        db.add(account)
        db.flush()

        order.current_balance = float(order.current_balance or 0) - total_deduction
        order.balance_before = balance_before
        order.balance_after = balance_after
        order.update_by = user_id
        order.update_time = now
        db.add(order)
        db.flush()

        _create_settlement_txn(
            db,
            order=order,
            schedule_id=schedule_id,
            application_no=application_no,
            amount=total_deduction,
            products_json=txn_products,
            balance_before=balance_before,
            balance_after=balance_after,
            tenant_no=tenant_no,
            user_id=user_id,
        )

    elif order_type == "gmcp":
        txn_products = []
        total_amount = 0.0
        for p in products:
            order_product = _find_service_order_product(db, order.id, p)
            if not order_product:
                label = p.project_name or p.cell_type_name or p.project_code or "未知产品"
                raise ValueError(f"服务订单中未找到匹配的产品持仓：{label}")

            project_code = order_product.project_code or ""
            spec_text = order_product.spec_text or ""
            qty = max(1, int(p.quantity or 1))

            cell_type_code, cell_type_name = _resolve_agreement_price_cell_type(
                db,
                order.channel_agreement_id,
                project_code,
                spec_text,
                order_product.cell_type or p.cell_type_name or "",
            )
            if not cell_type_code:
                cell_type_code = cell_type_name or (p.cell_type_name or "")

            _reduce_channel_product_quota(
                db,
                channel_id=order.channel_id,
                project_code=project_code,
                cell_type_code=cell_type_code,
                spec_text=spec_text,
                reduce_qty=qty,
                user_id=user_id,
            )

            current_qty = float(order_product.current_qty or 0)
            if current_qty < qty:
                raise ValueError(
                    f"订单产品「{order_product.project_name or project_code}」持仓不足，"
                    f"当前 {current_qty} 份，需扣减 {qty} 份"
                )
            order_product.current_qty = current_qty - qty
            order_product.update_by = user_id
            order_product.update_time = now
            db.add(order_product)
            db.flush()

            unit_price = float(order_product.agreement_unit_price or 0)
            if unit_price <= 0 and p.actual_price is not None:
                unit_price = float(p.actual_price)
            line_amount = unit_price * qty
            total_amount += line_amount
            txn_products.append(
                _schedule_product_to_txn_item(p, qty=qty, amount=line_amount)
            )

        _create_settlement_txn(
            db,
            order=order,
            schedule_id=schedule_id,
            application_no=application_no,
            amount=total_amount,
            products_json=txn_products,
            balance_before=None,
            balance_after=None,
            tenant_no=tenant_no,
            user_id=user_id,
        )

    else:
        raise ValueError(f"不支持的渠道服务订单类型：{order_type or '未知'}")


# ────────────────────────────────────────────
# Update schedule + products
# ────────────────────────────────────────────


def update_infusion_schedule_mgmt(
    db: Session,
    schedule_id: str,
    data: dict,
    tenant_no: str,
    user_id: str,
) -> Dict[str, Any]:
    row = (
        db.query(BizPilotInfusionSchedule)
        .filter(
            BizPilotInfusionSchedule.id == schedule_id,
            BizPilotInfusionSchedule.tenant_no == tenant_no,
            BizPilotInfusionSchedule.del_flag == 0,
        )
        .first()
    )
    if not row:
        raise ValueError("输注计划不存在")

    status = row.infusion_status or ""
    if status not in ("dtz", "yrqr"):
        raise ValueError("当前状态不允许编辑")

    now = datetime.now()

    fields = {
        "cellType": "cell_type",
        "specText": "spec_text",
        "packageId": "package_id",
        "packageText": "package_text",
        "infusionLocation": "infusion_location",
        "infusionMethod": "infusion_method",
    }
    for camel, snake in fields.items():
        if camel in data and data[camel] is not None:
            setattr(row, snake, data[camel])

    if "infusionTime" in data and data["infusionTime"] is not None:
        val = data["infusionTime"]
        if isinstance(val, str) and val:
            for fmt in ("%Y-%m-%d %H:%M:%S", "%Y-%m-%d %H:%M", "%Y-%m-%d"):
                try:
                    row.infusion_time = datetime.strptime(val, fmt)
                    break
                except ValueError:
                    continue

    row.update_by = user_id
    row.update_time = now

    products_data = data.get("products")
    if products_data is not None:
        def _price_id(item):
            return (item.get("priceId") or item.get("price_id") or "").strip()

        def _product_key(item):
            price_id = _price_id(item)
            if price_id:
                return "price:" + price_id
            project_code = (item.get("projectCode") or item.get("project_code") or "").strip()
            spec_text = (item.get("specText") or item.get("spec_text") or "").strip()
            return f"proj:{project_code}|{spec_text}"

        def build_product(row_id):
            return BizPilotInfusionScheduleProduct(
                id=row_id,
                infusion_schedule_id=schedule_id,
                tenant_no=tenant_no,
                create_by=user_id,
                create_dept_id="",
                create_time=now,
            )

        def apply_product(row, item, idx, _now):
            row.price_id = _price_id(item)
            row.project_code = item.get("projectCode") or item.get("project_code") or ""
            row.project_name = item.get("projectName") or item.get("project_name") or ""
            row.cell_type_name = item.get("cellTypeName") or item.get("cell_type_name") or ""
            row.spec_text = item.get("specText") or item.get("spec_text") or ""
            row.package_id = item.get("packageId") or item.get("package_id") or ""
            row.package_text = item.get("packageText") or item.get("package_text") or ""
            row.agreement_price = item.get("agreementPrice") if item.get("agreementPrice") is not None else (
                item.get("agreement_price") if item.get("agreement_price") is not None else None
            )
            row.actual_price = item.get("actualPrice") if item.get("actualPrice") is not None else (
                item.get("actual_price") if item.get("actual_price") is not None else None
            )
            row.quantity = item.get("quantity") if item.get("quantity") is not None else 1
            row.product_status = status
            row.order_num = idx + 1
            row.remark = item.get("remark") or ""

        sync_child_rows(
            db,
            BizPilotInfusionScheduleProduct,
            parent_attr="infusion_schedule_id",
            parent_id=schedule_id,
            tenant_no=tenant_no,
            items=list(products_data or []),
            user_id=user_id,
            now=now,
            build_row=build_product,
            apply_fields=apply_product,
            natural_key=_product_key,
            row_natural_key=lambda row: (
                "price:" + (row.price_id or "").strip()
                if (row.price_id or "").strip()
                else f"proj:{(row.project_code or '').strip()}|{(row.spec_text or '').strip()}"
            ),
            duplicate_message="输注产品重复",
            foreign_message="输注产品不属于当前计划",
        )

    db.commit()
    db.refresh(row)
    return get_infusion_schedule_detail(db, row.id, tenant_no)